'Global Leaders in Anaesthesia'

Administration of Dipivan (propofol) through TCI is currently restricted to induction and maintenance of general anaesthesia in adults. It is not recommended for use in ICU sedation or concious sedation, or in children.

Diprivan (propofol) may be administered by TCI only with a `Diprifusor` TCI system incorporating `Diprifusor` TCI software.

See the Diprifusor Monograph for more information.

Target control should be titrated against patient response to achieve required depth of anaesthesia. Guidelines are given below.

Induction of Anaesthesia

Patient Type
Adult <55yrs

Target Blood Propofol Concentration
4-8mcg/mL

Notes
Initial target of 4mcg/mL for premedicated patients. Initial target of 6mcg/mL for unpremedicated patients
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Patient Type
Adult >55yrs and ASA III/IV

Notes
Lower initial target should be used. Target concentrations can be increased in steps of 0.5-1.0mcg/mL over 1 minute intervals
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Maintenance of Anaesthesia Target Blood Propofol Concentration
3-6mcg/mL

Notes
Can be reduced by supplementary analgesia requirements
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Patient Type
Wakening

Target Blood Propofol Concentration
1.0-2.0mcg/mL


NOTE: For full details of product indications see local prescribing information